Michael R. Irwin
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Michael R. Irwin is an American academic and the Norman Cousins Chair of the Semel Institute for Neuroscience and Human Behavior at the University of California, Los Angeles. He is a Distinguished Professor of Psychiatry and Biobehavioral Sciences at the David Geffen School of Medicine at UCLA.[1][2][3][4]
Education and early life[edit]
Irwin was born and raised in a small town in rural Wyoming. He pursued his undergraduate studies at the College of arts and sciences at the University of Pennsylvania, where he obtained a degree in Biophysics in 1976.[5][6]
He began his medical training at the University of Colorado and completed it at the University of California, San Diego in 1981. He completed this psychiatry training at UCLA in 1985, including research training psychoneuroimmunology.[7]
Career[edit]
Irwin was a Professor of Psychiatry at University of California, San Diego (1985 to 2001), and was subsequently appointed Norman Cousins Professor of Psychiatry and Biobehavioral Science at UCLA. He currently serves as Director of the Cousins Center for Psychoneuroimmunology and Director of the Mindful Awareness Research Center.[8]
He was also the associate director of the Semel Institute for Neuroscience and Human Behavior (2019–2021) and Vice Chair of Research for the Department of Psychiatry and Biobehavioral Science (2019–2021).[9]
Irwin has served as an Associate Editor for three journals related to his research interests including Brain, Behavior, and Immunity, Psychosomatic Medicine and Sleep. He has held a leadership position as president for the PNIRS; Academy of Behavioral Medicine Research, and American Psychosomatic Society.[10][11][12]
Scientific contributions[edit]
Irwin has authored over 500 research articles. His early work examined the role of psychological stress in immune system function and resistance to cancer, and the central neuropeptide and adrenergic mechanisms by which the brain regulates immunity.[13][14][15]
His research has shown that interventions such as mindfulness meditation and tai chi can improve sleep quality, boost anti-viral immunity, and reduce systemic inflammation. Notably, his studies have indicated that treating insomnia can prevent depression, offering new avenues for preventive interventions in mental health.[16][17]
Awards and recognition[edit]
Irwin has received the Norman Cousins Award from the Psychoneuroimmunology Research Society, the Martica Hall Sleep Medicine Award from the American Psychosomatic Society, and the Charlton Award from Tufts University for his work in integrative medicine.[18]
PNIRS recognized his contributions and founded the Michael Irwin Equity and Diversity Awards 2020.[19]
Selected publications[edit]
- Irwin, M.; Caldwell, C.; Smith, T. L.; Brown, S.; Schuckit, M. A.; Gillin, J. C. (August 1990). "Major depressive disorder, alcoholism, and reduced natural killer cell cytotoxicity. Role of severity of depressive symptoms and alcohol consumption". Archives of General Psychiatry. 47 (8): 713–719. doi:10.1001/archpsyc.1990.01810200021003. ISSN 0003-990X. PMID 2378542.
- Irwin, M.; McClintick, J.; Costlow, C.; Fortner, M.; White, J.; Gillin, J. C. (April 1996). "Partial night sleep deprivation reduces natural killer and cellular immune responses in humans". The FASEB Journal. 10 (5): 643–653. doi:10.1096/fasebj.10.5.8621064. ISSN 0892-6638. PMID 8621064.
- Irwin, Michael R.; Wang, Minge; Campomayor, Capella O.; Collado-Hidalgo, Alicia; Cole, Steve (18 September 2006). "Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation". Archives of Internal Medicine. 166 (16): 1756–1762. doi:10.1001/archinte.166.16.1756. ISSN 0003-9926. PMID 16983055.
- Irwin, Michael R.; Olmstead, Richard; Breen, Elizabeth C.; Witarama, Tuff; Carrillo, Carmen; Sadeghi, Nina; Arevalo, Jesusa M. G.; Ma, Jeffrey; Nicassio, Perry; Bootzin, Richard; Cole, Steve (15 November 2015). "Cognitive behavioral therapy and tai chi reverse cellular and genomic markers of inflammation in late-life insomnia: a randomized controlled trial". Biological Psychiatry. 78 (10): 721–729. doi:10.1016/j.biopsych.2015.01.010. ISSN 1873-2402. PMC 4524803. PMID 25748580.
- Irwin, Michael R.; Carrillo, Carmen; Sadeghi, Nina; Bjurstrom, Martin F.; Breen, Elizabeth C.; Olmstead, Richard (1 January 2022). "Prevention of Incident and Recurrent Major Depression in Older Adults With Insomnia: A Randomized Clinical Trial". JAMA Psychiatry. 79 (1): 33–41. doi:10.1001/jamapsychiatry.2021.3422. ISSN 2168-6238. PMC 8733847. PMID 34817561.
- Slavich, George M.; Irwin, Michael R. (May 2014). "From stress to inflammation and major depressive disorder: A social signal transduction theory of depression". Psychological Bulletin. 140 (3): 774–815. doi:10.1037/a0035302. PMC 4006295. PMID 24417575.
- Black, David S.; O’Reilly, Gillian A.; Olmstead, Richard; Breen, Elizabeth C.; Irwin, Michael R. (1 April 2015). "Mindfulness Meditation and Improvement in Sleep Quality and Daytime Impairment Among Older Adults With Sleep Disturbances: A Randomized Clinical Trial". JAMA Internal Medicine. 175 (4): 494–501. doi:10.1001/jamainternmed.2014.8081. ISSN 2168-6106. PMC 4407465. PMID 25686304.
References[edit]
- ^ "Cousins - Semel Institute for Neuroscience and Human Behavior". Semel Institute for Neuroscience and Human Behavior.
- ^ Gorham, Meg. "Awards & Lectures". www.pnirs.org.
- ^ Smith, Stephen (13 February 2007). "Embrace your siesta for a healthy heart - Health & Science - International Herald Tribune". The New York Times.
- ^ "How to Get Better Sleep When You Have IBD". Time (magazine). 11 April 2023.
- ^ "Michael Irwin, M.D. – UCLA Brain Research Institute (BRI)". Semel Institute for Neuroscience and Human Behavior.
- ^ Hasan, Nafis (10 October 2017). "Michael Irwin, MD, to deliver 42nd Charlton Lecture, Oct 25". Tufts University.
- ^ "Dr. Martica Hall Award in Sleep Medicine". American Psychosomatic Society.
- ^ "Psychoneuroimmunology, Norman Cousins Center for PNI at UCLA -- Weiner Biography". The Cousins Center for Psychoneuroimmunology.
- ^ "Michael Irwin, M.D." Best Doctors in America. 23 January 2017.
- ^ "Leadership". Academy of Behavioral Medicine Research.
- ^ "Past Presidents". American Psychosomatic Society.
- ^ Gorham, Meg. "Awards & Lectures". www.pnirs.org.
- ^ "To boost immunity, forget 'magic pills.' Focus on sleep, exercise, diet and cutting stress". The Washington Post.
- ^ "Frisca L. Yan-Go, MD Lectureship in Sleep Medicine". www.uclahealth.org.
- ^ Gleeson, Scott. "Clinical study shows therapeutic sleep training for older adults can prevent depression". USA Today.
- ^ LaMotte, Sandee (24 November 2021). "Sleep training for adults prevents depression, study finds". CNN.
- ^ "CBT Prevents Depression in Up to 50% of Patients With Insomnia". Medscape.
- ^ "ESIM AWARD". European Society for Integrative Medicine.
- ^ "Meeting Awards". PNIRS.